Pharma & Biotech

AI Platform for CNS-Targeted Therapeutic Discovery

Unified scientific platform for multimodal protein data, predictive modeling, and generative therapeutic design.

100%

De-novo protein design

400

Proteins generated

27

Proteins narrowed down for experimental validation.

Customer Stories

A clinical-stage biotech company needed a unified scientific platform to support CNS therapeutic development.

Biotech

Industry

USA

Location

ML System Design & Predictive Engines, Data Engineering, Platform Engineering, Scientific UX & Explainability

Services

Under NDA

Budget

Challenge

Client’s data was fragmented across expression datasets, literature notes, protein atlases, and internal assays. Predictive modeling and generative design workflows required heavy manual input from scientific teams, slowing target evaluation and limiting scalability.

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Outcomes We Deliver

Solution

We designed and engineered an end-to-end AI platform that merges scientific data engineering, predictive modeling, generative design, and LLM-based reasoning into a single product architecture.

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Dalriada
Tech Stack

To build an end-to-end AI platform that merges scientific data engineering, Blackthorn AI applied:

Python
FastAPI
PyTorch
OpenAI
React
TypeScript
Three.js
Apache Airflow
PostgreSQL
GCP
Docker
GitHub
Roadmap

Project duration

01–08 Weeks

Data Infrastructure & Knowledge Base

Integration of multimodal scientific datasets into a Unified Knowledge Base, construction of a biomedical knowledge graph (proteins, genes, expression data, transport mechanisms), frontend/backend integration of structure prediction tools (AlphaFold-class models).

08–16 Weeks

Predictive Modeling Layer

Development of ML models for: BBB penetration prediction, carrier–protein binding, receptor–ligand interaction scoring.Integration of GNNs, protein language models, and physics-based refinement tools.

16–20 Weeks

Generative Therapeutic Design Engine

Integration of modality-specific generative models: peptide design, antibody sequence generators, small-molecule diffusion models

20–24 Weeks

Validation Analytics & XAI Layer

Explainability module for model outputs, benchmarking against client’s internal datasets, scientific visualization layer for interaction networks, technical documentation & reproducibility toolkits

Team Size

6 team members from Blackthorn.ai
1 x Solution Architect
1 x Senior Bioinformatics Engineer
1 x Machine Learning Engineer
1 x Data Engineer
1 x Full-stack Developer
1 x DevOps / MLOps

Delivering Impact

Beyond the values already highlighted, there’s even more to discover. Our commitment to innovation, client success, and impactful results sets us apart

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400

Proteins generated

Each protein was computationally evaluated for folding integrity, functional relevance, and design novelty, enabling rapid exploration of a large sequence space that would be impractical to screen manually.

27

Proteins narrowed

Down for experimental validation.

100%

De-novo protein design

Our platform achieved 100% fully automated de-novo protein design, generating novel protein sequences directly from biochemical constraints and target-specific requirements.

35%

Acceleration

Of early lead-optimization cycles

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