About this event
We aim to meet your research needs. Visit numerous concurrent sessions all week for informative presentations, lively dialogue, and meaningful connections with peers. Customize your experience further through focused short courses, training seminars, interactive breakout discussions, and networking options that help you engage with experts and solutions providers.
Our four-day event brings back popular topics like kinases, immunomodulation, and degraders, plus new coverage of covalent chemistries and induced proximity, synthetic biology, cancer antibodies, generative AI, and translational models.
The 22nd Annual Discovery on Target (DOT) event will take place from September 30 to October 3, 2024, in Boston, MA, organized by the Cambridge Healthtech Institute. This conference focuses on the latest advancements in drug discovery, covering topics such as kinase targeting, covalent chemistries, immune modulation strategies, synthetic biology, degraders, molecular glues, and AI/ML-enabled drug discovery. It offers attendees the opportunity to learn about cutting-edge strategies for target validation and the development of therapeutic agents, including biologics and small molecules.
Agenda
September 30:
Strategies for Targeting Kinases
Covalent Chemistries and Induced Proximity
Emerging Immune Modulation Strategies
Synthetic Biology for Drug Discovery and Therapy
October 1-2:
Degraders and Molecular Glues – Part 1
Lead Generation Strategies
Small Molecules for Cancer Targets
Antibodies Against Membrane Protein Targets
Small Molecules Targeting RNA
AI/ML-Enabled Drug Discovery – Part 1
Physiologically Relevant Translational Models
GPCR Pharmacodynamics: Kinetics, Allosterism, and Biased Agonism in Pharma Discovery
October 2-3
Degraders and Molecular Glues – Part 2
Target Identification Strategies
GPCR-Based Drug Discovery
Cancer Antibodies
Targeting Transcription Factors
AI/ML-Enabled Drug Discovery – Part 2
Drug Exposure at the Target: The Role of ADME and Pharmacokinetics
