Pharma & Biotech

Debut Biotechnology Inc

Generation of hit-like molecules from transcriptomics data, predicting compound activity, and pathway analysis for novel therapies in skin rejuvenation.

Customer

Our client is a leading CRO for turnkey small molecule drug discovery. The company offers global biotechnology and pharmaceutical companies a full suite of drug discovery expertise and state-of-the-art R&D operations converting promising scientific discoveries into life-transforming therapies.

Challenge

A biotech startup struggled with selection of novel small molecules with desired biological activity.

Business goals

Reduce the cost and speed up the early drug discovery phase by reducing the number of candidate molecules synthesized at the preclinical research stage.

Results/ Benefits

Our team helped select several thousand candidates with expected skin rejuvenation activity in several months of work. 453 of these small molecules confirmed their activity in the subsequent wet lab experiments, saving the customer years of research and millions USD of budget.

Team

  • Research Lead
  • Bioinformatician
  • AI Research Engineer

Technologies

  • R
  • Python
  • PyTorch
  • LLM
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Alex Gurbych

Alex Gurbych

Chief Solutions Architect

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