Healthcare

POST-COVID EFFECTS AND IMMUNOLOGICAL MARKERS OF AGING

Proceedings of the Shevchenko Scientific Society. Medical Sciences Volume 76, Issue 2
27.12.2024
Iryna Kril, Valentyna Chopyak, Natalia Melnykova, Andriy Bazylevych, Natalia Shakhovska
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This paper investigates the post-COVID effects on the immune system, particularly focusing on aging populations. It discusses the role of immune-competent cells, especially T-lymphocytes, in COVID-19 patients and how their decrease contributes to immune system dysfunction. The study highlights how COVID-19 exacerbates chronic conditions common in older adults, such as chronic pain, inflammation, and mental health disorders, including Alzheimer’s disease and PTSD. The research also explores how COVID-19 induces a “cytokine storm” that accelerates aging processes and immune system decline, with artificial intelligence being employed to analyze patient data for predicting accelerated aging post-infection.

Takeaways:

  1. Impact of COVID-19 on Elderly Immunity: Older adults experience a more severe decline in T-cell function post-COVID, contributing to both physical and mental health challenges.
  2. Cytokine Storms and Aging: COVID-19-induced cytokine dysregulation weakens the immune system, particularly in the elderly, accelerating the aging process.
  3. Mental Health Considerations: Elderly COVID-19 patients are at heightened risk for mental health disorders, including cognitive decline and PTSD, post-infection.
  4. AI for Prognosis: Artificial intelligence has proven useful in analyzing patient data to predict the long-term effects of COVID-19, particularly in aging individuals.
  5. Immune System and Aging Biomarkers: Alterations in immune markers linked to COVID-19 severity can be used to assess disease progression and predict rehabilitation outcomes.

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